Parkinson's Disease. Parkinson's disease
Conditions
Interventions
The intervention group will take an oral capsule containing probiotics for 8 weeks before going to bed. Both groups will receive nutritional training and non-pharmacological strategies for treating co
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with Idiopathic Parkinson Disease With Rome IV criteria for functional constipation Age equal to or above 60 years Agreed to sign the informed written consent
Exclusion criteria
Exclusion criteria: There is a contraindication to probiotics, such as previous allergies to it Patients with active infection diagnosis Patients being treated with antibiotics. Patients less than 60 years Patients receiving other probiotics Patients who regularly use laxatives Patients who are immunocompromised Patients who are receiving traditional medicine products to relieve constipation. Patients who are receiving drugs that have a high risk of constipation in the complication profile with a high risk of 10%. (Except for FDA approved drugs in the treatment of Parkinson's)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of defecation per week. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet. | — |
Secondary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale (UPDRS). Timepoint: The beginning of the study and the end of the study. Method of measurement: Unified Parkinson's Disease Rating Scale (UPDRS) Questionnaire.;Defecation consistency. Timepoint: The beginning of the study and the end of the study. Method of measurement: Bristol stool scale.;Sensation of complete evacuation. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet.;Frequency of medication interventions to improve constipation. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHadi Esmaily
Shahid Beheshti University of Medical Sciences
Outcome results
None listed