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Effect of gabapentin capsules on nausea and vomiting

The effect of gabapentin capsules on reduction of nausea and vomiting after chemotherapy in patients admitted in adult hematology section in platinum-

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017060734381N1
Enrollment
120
Registered
2017-07-23
Start date
2017-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer. Malignant neoplasm of stomach, Malignant neoplasm of small intestine, Malignant neoplasm of colon, Malignant neoplasm of rectosigmoid junction, Malignant neoplasm of rectum

Interventions

Intervention 1: In the intervention group: gabapentin capsule of 300 milligrams three times a day from one day Chemotherapy will be used until the end of the chemotherapy period. Intervention 2: In th
Treatment - Drugs
In the intervention group: gabapentin capsule of 300 milligrams three times a day from one day Chemotherapy will be used until the end of the chemotherapy period.
In the control group, for the reduction of nausea and vomiting after chemotherapy, a routine of three drugs (dexamethasone, ranitidine and ketril) will be used

Sponsors

Ahvaz Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: : Patients receiving chemotherapy regimen. Exclusion criteria: history of seizure or epilepsy; nausea and vomiting; gabapentin susceptibility; severe illness along with cancer (cardiac, kidney, liver and etc.).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting. Timepoint: after intervention. Method of measurement: By grade.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Shayesteh

Ahvaz Jundishapur University of Medical Sciences

shayesteli@yahoo.com+98 61 3292 1839

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026