Evaluating the effect of high dose versus low dose of heparin in patency of peripherally inserted central catheter in very low birth weight infants in alzahra and shahid beheshti hospitals in Isfahan at 1395-1396

Optimal dose of heparin for patency of peripherally inserted central catheter

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017060621910N3

Enrollment

Registered

2017-06-16

Start date

2015-12-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Neonatal Sepsis. Condition 2: Intra Ventricular Hemorrhage. Condition 3: Catheter Related Sepsis. Condition 4: Phlebitis. Bacterial sepsis of newborn, unspecified Intracranial (nontraumatic) haemorrhage of fetus and newborn, unspecified Unspecified complication of cardiac and vascular prosthetic device, implant and graft Other specified complications of cardiac and vascular prosthetic devices, implants and grafts

Interventions

Intervention 1: In Intervention Group we prescribed 1/5 u/kg/h of Heparin Via PICC. Intervention 2: In Control Group we prescribed ./5 u Heparin/1 cc of Serum Via PICC.

Prevention

In Intervention Group we prescribed 1/5 u/kg/h of Heparin Via PICC

In Control Group we prescribed ./5 u Heparin/1 cc of Serum Via PICC

Eligibility

Sex/Gender

All

Age

No minimum to 1 Months

Inclusion criteria

Inclusion criteria: Inclusion criteria: preterm infants with birth weight less than 1500 gram; An informed consent obtained from patients parents; infant needs total parentral nutrition; long-term IV medication administration; administration of hyperosmolar IV fluids. Exclusion criteria: Skin infection at insertion site; uncorrected bleeding diathesis; ongoing bacteremia or fungal infection; follow up impossibility during study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Duration of Catheter Patency. Timepoint: Daily. Method of measurement: With Normal Saline and 5 cc Syringe.	—

Secondary

Measure	Time frame
Catheter Related Sepsis. Timepoint: during Study. Method of measurement: Culture of Catheter Tip.;Intra Ventricular Hemorrahge. Timepoint: 3th and 14th and 21th days. Method of measurement: Brain Sonography.;Phlebitis. Timepoint: During Study. Method of measurement: Observation and Physical Examination.;Sepsis. Timepoint: During Study. Method of measurement: Clinical Sign and Blood Culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLadan Salamaty

Isfahan University of Medical Sciences

ladan_salamaty@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026