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Effect of Chlorella supplementation on Dysmenorrhea

Effect of Chlorella supplementation on systematic symptoms and serum levels of prostaglandins, inflammatory and oxidative markers in women with primary dysmenorrhea

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017060610181N11
Enrollment
44
Registered
2017-07-07
Start date
2017-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary Dysmenorrhea. Primary dysmenorrhoea

Interventions

Intervention 1: Intervention group: soft gel Chlorella , 300 mg, 5 per day for 2 months. Intervention 2: Control group: placebo Soft gel , 5 per day for 2 months.
Treatment - Drugs
Placebo
Intervention group: soft gel Chlorella , 300 mg, 5 per day for 2 months
Control group: placebo Soft gel , 5 per day for 2 months

Sponsors

Vice chancellor for research of Ahvaz University of Medical sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having regular menstrual periods, moderate or severe dysmenorrheal and being single Exclusion criteria: pain throughout the menstrual cycle, sensitivity to non-steroidal anti-inflammatory drugs, use of any antioxidant supplements in the past three months, taking oral contraceptives, reproductive disorders and a history of any abdominal or pelvic surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
PGE2. Timepoint: Before and after the intervention. Method of measurement: Pg/ ml by ELISA.;PGF2a. Timepoint: Before and after the intervention. Method of measurement: Pg/ ml by ELISA.;Hs-CRP. Timepoint: Before and after the intervention. Method of measurement: µg/ml by ELISA.;MDA. Timepoint: Before and after the intervention. Method of measurement: µmol/l by TBARS.;Severity of pain. Timepoint: Before and after the intervention. Method of measurement: Using Visual Analog Scale.;Duration of pain. Timepoint: Before and after the intervention. Method of measurement: namber of Days and hours of pain in cycle.;Systemic symptoms. Timepoint: Before and after the intervention. Method of measurement: verbal multidimensional system questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Fatemeh Haidari

Ahwaz University of Medical Sciences

haidari58@gmail.com+98 61 3333 9092

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026