Cognitive impairment.
Conditions
Interventions
Control group: Control group: Memantine in the case group starts 24 hours before the start of the study with a dose of 10 mg and will increase to 20 mg in a week. And will continue until the end of se
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: In this clinical trial, 60 patients over the age of 18 and under the age of 60 with bipolar disorder psychiatric illnesses will be admitted to the ECT since the beginning of the year 1396-97.All patients will undergo a full psychiatric assessment and patient disorder is recorded based on DSM-V.
Exclusion criteria
Exclusion criteria: Age outcomes aged less than 18 years and over 60 years of age, alcohol dependence or drug and drug addiction (except nicotine and caffeine) within 3 months of admission, confirmed kidney disease, epilepsy, back Mental retardation, cognitive impairments such as delirium and dementia, history of memantine use in the past 3 months before entering the study, patients who are unable to perform tests due to distraction , gastrointestinal disturbances and memantine susceptibility, and during Studying or suffering from intolerance to increasing the dose of memantine, as well as patients who receive more than 6 ECT sessions, are excluded be.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The cognitive ability of the patients will be measured 24 hours before and 24 hours after the ECT session 6, as well as one month after the completion of the ECT using the MMSE (Mini Mental Status Examination) and the Aden Brook Cognitive Examination Test. We will use the MMSE Iranian version in this study. Timepoint: 24 hours before and 24 hours after the 6th session of the ECT, as well as one month after the completion of the ECT. Method of measurement: Eden Brook MMSE (Mini Mental Status Examination). | — |
Secondary
| Measure | Time frame |
|---|---|
| As well as one month after the completion of the ECT using the MMSE (Mini Mental Status Examination) and the Aden Brook Cognitive Examination Test. We will use the MMSE Iranian version in this study. Timepoint: One month after the completion of the ECT. Method of measurement: In this research we will use the Iranian version of MMSE and Eden Brooke. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Angela Hamidia
Babol University of Medical Sciences
Outcome results
None listed