The effect of 30 mg oral dextromethorphan and placebo on postoperative analgesia after laparoscopic cholecystectomy

The effect of 30 mg oral dextromethorphan and placebo on postoperative analgesia after laparoscopic cholecystectomy at the Hamedan Besat hospital

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170603034303N3

Enrollment

114

Registered

2019-08-28

Start date

2019-08-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis. Chronic cholecystitis

Interventions

Intervention 1: Intervention group: 30 mg or 10 cc of dextromethorphan syrup 2 hours before induction of anesthesia used. Intervention 2: Control group: 10 cc of a neutral syrup 2 hours before inducti

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with ASA class 1 and 2 Patients candidate for laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Patients with systemic underlying disease Patients with history of alcohol and drug use, sedation and anticonvulsants History sensitivity to drugs

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1, 6 and 12 hours after surgery. Method of measurement: VAS score.	—

Secondary

Measure	Time frame
Nausea & vomiting. Timepoint: After surgery. Method of measurement: Observation.;Systolic and Diastolic Blood Pressure. Timepoint: 1 hours after surgery. Method of measurement: Barometer.;Heart Rate. Timepoint: 1 hours after surgery. Method of measurement: Using a pulse oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mahmoud Rezaeei

Hamedan University of Medical Sciences

m.rezaeei@umsha.ac.ir+98 81 3827 7012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026