Irreversible pulpitis. Diseases of pulp and periapical tissues, Pulpitis
Conditions
Interventions
Intervention 1: intervention group:
1.8 mL of 4% articaine with clonidine (A+Clo) at a concentration of 15 µg/mL applied by using conventional inferior alveolar nerve block injection technique. Interv
Treatment - Drugs
intervention group:
1.8 mL of 4% articaine with clonidine (A+Clo) at a concentration of 15 µg/mL applied by using conventional inferior alveolar nerve block injection technique.
control group :
1.8 mL of 4% articaine with epinephrine 1:100000 (A+Epi) applied by using conventional inferior alveolar nerve block injection technique.
Sponsors
Vice Chancellor for research of Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria: 18 years of age up to 60; in good health(ASA I (classification of the American Society of Anesthesiologists)); having at least one mandibular molar tooth with irreversible pulpitis criteria The exclusion criteria: Patients taking beta-blockers or being medicated with any opioids preoperatively; drug abusers; pregnant or nursing mothers; those with a contraindication for the use of clonidine; those known to be allergic to clonidine; those with orofacial infection
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: penetrate the dentin, entering the pulp chamber and initial file placement. Method of measurement: Heft-Parker visual analogue scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Masoud Saatchi
Isfahan University of medical sciences
Outcome results
None listed