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The Effect Of Ondansetron on maternal hypotension prevention during elective cesarean section

Efficacy of intravenous ondansetron in preventing hypotension in patients undergoing elective cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201706015381N12
Enrollment
80
Registered
2017-06-21
Start date
2017-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maternal hypotension. Maternal hypotension syndrome

Interventions

Intervention 1: Control group: 2 mm distilled water was injected intravenously before spinal anesthesia. Intervention 2: Intervention group: 4 mg ondansetron ( Norman/Italy) was injected intravenousl
Prevention
Control group: 2 mm distilled water was injected intravenously before spinal anesthesia
Intervention group: 4 mg ondansetron ( Norman/Italy) was injected intravenously before spinal anesthesia

Sponsors

Vice chancellor research for Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Pregnant women (18 to 35 years old) Candidate for elective cesarean section, In class I physical health classification of the American Society of Anesthesia. All women had singleton term pregnancies. Exclusion Criteria: Mothers with a history of hypertension? Diabetes? cardiovascular and cerebral diseases? known fetal anomaly? any kind of contraindications for spinal anesthesia? psychosomatic Disorder? Patients weighting over 100 Kg and Height less than 150 cm and those with difficult tracheal intubation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Maternal blood presure. Timepoint: Maternal blood pressure was monitored and recorded every two minutes for the first 15 minutes following spinal anesthesia, and then every 5 minutes until completion of surgery. Method of measurement: Non invasive blood presure cuff.

Secondary

MeasureTime frame
Maternal heart rate. Timepoint: during surgery. Method of measurement: With cardiac monitoring and heart rate.;Neonatal arterial blood gas. Timepoint: After Surgery. Method of measurement: Arterial blood gas samples.;Neonatal apgar score. Timepoint: 1 and 5 minutes after surgery. Method of measurement: Cheklist/ examination/ observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nadia Banihashem

Babol University of Medical Sciences

nbanihashem@yahoo.com+98 11 3223 8284

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026