Effect of two treatment protocols of balloon dilatation and administration of methotrexate in tracheal stenosis due to intubation

Comparison of the Effectiveness of two treatment protocols of balloon dilatation and administration of methotrexate as an auxiliary treatment for patients with tracheal stenosis due to intubation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170531034256N3

Enrollment

Registered

2020-02-04

Start date

2019-03-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with tracheal stenosis due to intubation. Other specified diseases of upper respiratory tract

Interventions

Intervention 1: Intervention group: Methotrexate will be used every two weeks and patients will be followed every week in the first month and then at month 3 and 6. Intervention 2: Control group: They

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a diagnosis according to the results of medical and paraclinical examinations Patients with tracheal stenosis caused by intubation

Exclusion criteria

Exclusion criteria: congenital tracheal stenosis as well as tracheal stenosis are excluded. Patients with tracheal stenosis due to primary or metastatic malignancies Patients with tracheal stenosis due to vasculitis such as Wegener's disease

Design outcomes

Primary

Measure	Time frame
Need for surgical treatment at follow-up. Timepoint: Every week in the first month- month 3- month 6. Method of measurement: Physician diagnosis.	—

Secondary

Measure	Time frame
Side effects. Timepoint: every week in the first month- month 3- month 6. Method of measurement: Interview - Examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegar Bandegani

Shahid Beheshti University of Medical Sciences

Fatemehrazavi@sbmu.ac.ir+98 21 2712 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026