Preterm labour. Preterm labour without delivery
Conditions
Interventions
Intervention 1: Interventions group: 80 mg of aspirin daily (bedtime) in combination with folic acid + iron tablets from the second trimmest will be prescribed to patients
To apply rigorous random as
Treatment - Drugs
Interventions group: 80 mg of aspirin daily (bedtime) in combination with folic acid + iron tablets from the second trimmest will be prescribed to patients
To apply rigorous random assignment, in th
Controls group: Daily folic acid with placebo (Consisting of sugar and starch that the shape, size and color is quite similar to aspirin) + iron tablets will be prescribed to patients.
Sponsors
Vice Chancellor for Research and Technology, Semnan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 18 to 40 years; nulliparous; the singleton pregnancy is between 12 to 13 weeks of pregnancy that is confirmed to medical ultrasound; less than 2 miscarriage in the first 3 months of pregnancy. Exclusion criteria: history of loss pregnancy in second trimester; contraindication of aspirin usage; smoking and drugs usage; multiple pregnancy; visible fetal anomalies by medical ultrasound; hemoglobin level less than 7 milligram per deciliter; previous risk of systemic diseases; individuals with short cervical length less than 25 millimeter; uterine anomalies.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of cervical length. Timepoint: Week 13 and week 30 of pregnancy. Method of measurement: Transvaginal ultrasound.;Blood hemoglobin. Timepoint: Week 13 and week 30 of pregnancy. Method of measurement: Complete Blood Counter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhgan Rahmanian
Semnan University of Medical Sciences
Outcome results
None listed