Generalized vitiligo. Vitiligo
Conditions
Interventions
Intervention 1: Photo therapy using NB-UVB with initial dose of 0.25 J/cm2 three sessions in a week plus 8-Metoxi Pesoralen with dose of 0.6mg/kg two hours before photo therapy. Intervention 2: Photo
Treatment - Drugs
Photo therapy using NB-UVB with initial dose of 0.25 J/cm2 three sessions in a week plus 8-Metoxi Pesoralen with dose of 0.6mg/kg two hours before photo therapy.
Photo therapy using 0.6mg/kg with initial dose of 0.25 J/cm2 three sessions in a week
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
13 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with generalized Vitiligo who have 5 to 60 percent body involvement; filling out consent form by patient; age over 13 years old Exclusion criteria: patients who have been under phototherapy or photochemotherapy during 3 months before study starts; patients who have had over 100 phototherapy or photochemotherapy sessions before; pregnancy or breast feeding; heart, kidney and liver disease; children under 13 years old; history of photosensitivity or any dermatosis created by UV light like Lupus Erythematosus; history of previous skin malignancy; history of cataract
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extent of lesion. Timepoint: Before starting treatment and after each 20 sessions. Method of measurement: Taking photos and measuring in hand unit and each hand unit is equal to 1 percent. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Zahra Ashrafi
Mashhad University of Medical Sciences
Outcome results
None listed