effectiveness of subcotaneous injection of piroxicam compared with oral use of piroxicam in pain improvement in patients with knee osteoarthritis.

clinical trial comparing the effect of oral piroxicam and subcotaneus injection of piroxicam(mesotherapy) on improvement of pain and function in patients with knee osteoarthriris.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017052434113N1

Enrollment

Registered

2017-09-19

Start date

2017-09-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arthrosis. primary gonarthrosis,bilateral

Interventions

Intervention 1: group1intervention:subcotaneus injection of 20mgpiroxicam with 5cc lidocain2% around knee,repeat 10days later,life style modification and knee exercise. Intervention 2: group 2 interve

Treatment - Drugs

group1intervention:subcotaneus injection of 20mgpiroxicam with 5cc lidocain2% around knee,repeat 10days later,life style modification and knee exercise.

group 2 intervention:oral use of 20 mg piroxicam for 10 days,life style modification,exercise for knee.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria:40-70y/o patients with mild to moderate osteoarthritis with clinical symptoms at least recent 1month; exclusion criteria:disease suchvas:DM,collagen vascular and rheumatism,gout,neuropathy,radiculopathy,nerve injury,brucella,BMI>42,trauma ,bleeding tendency,significant hepatic,renal and cardiopulmonaryproblems,knee arthroplasty,allergy to piroxicam,knee injection in recent 3month,pregnancy,cancer,cognitive disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain improvement. Timepoint: befor intervention,2and4weeks after intervention. Method of measurement: VAS,WOMAC,AXFORD questionnaires.	—

Secondary

Measure	Time frame
Improvement in function. Timepoint: before intervention,2 and 4 weeks after intervention. Method of measurement: VAS,WOMAC,AXFORD questionnaires.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfahime estakhri

shiraz university of medical science

estakhrif@sums.ac.ir+98 71 3230 5410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 19, 2026