The effect of pregabalin on post dural puncture headache.

Assessment of Pregabalin Effects on Post-Dural Puncture Headache After Spinal Anesthesia in Elective Cesarean Surgery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170516033992N4

Enrollment

136

Registered

2020-12-26

Start date

2019-12-16

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headach. Headache

Interventions

Intervention 1: Intervention group: pregnant women, candidates for elective cesarean section were prescribed 150 mg pregabalin capsule made by Pfizer 90 minutes before preparation for surgery. Interve

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant women who undergo elective cesarean section American Society of Anesthesiologists (ASA) 1 and 2

Exclusion criteria

Exclusion criteria: Having a history of migraine The patient with ASA 3 and above The patients with indications for emergency cesarean section Previous history of post-dural puncture headache Prohibitions of spinal anesthesia for patients who are unable to cooperate

Design outcomes

Primary

Measure	Time frame
Severity of headach. Timepoint: Evaluation of the incidence and Severity of post-dural puncture headache in the interval of 6,12, 24, 48, 72 hours after spinal anesthesia. Method of measurement: Visual analog scale.	—

Secondary

Measure	Time frame
Post-dural puncture headache. Timepoint: 6,12, 24, 48, 72 hours after spinal anesthesia. Method of measurement: Visual analog scale.;. Timepoint: . Method of measurement: .	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTohid Karami

Oroumia University of Medical Sciences

karami.tohid@gmail.com+98 44 3193 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026