Comparison of the effects of propofol - ketamine and propofol- fentanyl drug regimens on sedation in endoscopy

Comparison of the effects of propofol - ketamine and propofol- fentanyl drug regimens on sedation in children undergoing upper endoscopy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170516033992N13

Enrollment

Registered

2023-03-30

Start date

2023-05-22

Completion date

Unknown

Last updated

2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation during endoscopy. Failed moderate sedation during procedure

Interventions

Intervention 1: Intervention group: In the first group, induction of anesthesia will be performed with 0.05 mg/kg of midazolam, 1 mg/kg of propofol, 1 mg/kg of ketamine and 0.02 mg/kg of atropine and

Eligibility

Sex/Gender

All

Age

1 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children undergoing upper endoscopy Age between 1-10 years

Exclusion criteria

Exclusion criteria: Emergency endoscopies Patients who do not fast for 6 hours. Patients with a disease history such as cerebral palsy or neuromuscular disorders

Design outcomes

Primary

Measure	Time frame
Sedation score. Timepoint: During endoscopy. Method of measurement: Evaluation by the endoscopist.	—

Secondary

Measure	Time frame
Recovery time. Timepoint: After induction of anesthesia. Method of measurement: Minute.;Need for additional anesthesia drug. Timepoint: After induction of anesthesia. Method of measurement: No/yes.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Tohid Karami

Oroumia University of Medical Sciences

karami.t@umsu.ac.ir+98 44 3223 7077

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026