Skip to content

Studying the intravenous lidocaine infusion effect on pain

Studying the intravenous lidocaine infusion effect on pain in patients undergoing femoral neck fracture surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170516033992N12
Enrollment
64
Registered
2022-11-29
Start date
2022-12-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of neck of femur. Fracture of neck of femur

Interventions

Intervention 1: Intervention group: First, all patients will receive intravenous midazolam (0.05 mg/kg) and intravenous fentanyl (2 µg/kg) as premedication. 5 minutes later, propofol 2 mg/kg and atrac
firstly, 1.5 mg/kg intravenously of lidocaine solution 1% will be injected
then the infusion of lidocaine 1% with a dose of 2 mg/kg per hour will be started with a syringe pump infusion device. Intervention 2: Control group: First, all patients will receive intravenous midaz

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients undergoing femoral neck fracture surgery Age between 18 to 85 years Patients with physical status one and two according to the criteria of the American Anesthesia Association (ASA I, II)

Exclusion criteria

Exclusion criteria: History of allergy to local anesthetics Use of opioids and analgesics Use of steroids Pregnancy A history of heart failure Having liver and kidney diseases Uncontrolled blood pressure Endocrine diseases Body mass index (BMI) above 40 kg/m2

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: Recovery, 6, 12 and 24 hours after the intervention. Method of measurement: Visual Analog Scale (VAS ).

Secondary

MeasureTime frame
Administration of fentanyl as analgesic. Timepoint: During 24 hours after the intervention. Method of measurement: no, yes.;Systolic blood pressure. Timepoint: Before, recovery, 6, 12 and 24 hours after the intervention. Method of measurement: monotring.;Diastolic blood pressure. Timepoint: Before, recovery, 6, 12 and 24 hours after the intervention. Method of measurement: monotring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Tohid Karami

Oroumia University of Medical Sciences

karami.t@umsu.ac.ir+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026