Delirium. Sedative, hypnotic or anxiolytic use, unspecified with withdrawal delirium
Conditions
Interventions
Intervention 1: Intervention group: 8 mg of Intravenous ondansetron. Intervention 2: Control group: 8 mg of intravenous normal saline.
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with age over 60 years Patients with ASA I and ASA II Patients candidate of hip and proximal femoral fracture surgery
Exclusion criteria
Exclusion criteria: Patients with a history of dementia, Alzheimer, Parkinson or other neurological disorders Alcohol usage Patients with a history of hearing and speech disorders Patients with a history of receiving of anti-depression and sedatives drugs Duration of surgery more than 3 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: 4- point scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea. Timepoint: Recovery,30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination.;Vomoting. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Leakage of stomach contents.;Pruritus. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination.;Shivering. Timepoint: Recovery, 30 minutes, one hour, 6 hours, 8 hours and 24 hours after surgery. Method of measurement: Clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Nazli Karami
Oroumia University of Medical Sciences
Outcome results
None listed