Burn. Burns and corrosions of external body surface, specified by site
Conditions
Interventions
Intervention 1: Intervention: a 60 mg oral capsule of duloxetine per day. Intervention 2: Control: No treatment.
Treatment - Drugs
Intervention: a 60 mg oral capsule of duloxetine per day
Sponsors
Vice chancellor for research, Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Burn patients requiring hospitalization for at least one week Exclusion criteria: Bipolar mood disorder; consuming monoamine oxidase inhibitor drugs, three cyclic antidepressant drugs, tramadol, buspirone, triptan drugs, lithium, ondansetron, potent inhibitors of cytochrome P450 (CYP450) 2D6 and CYP450 1A2; creatinine clearance less than 30 ml per minute; hepatic failure; uncontrolled epilepsy; thrombocytopenia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: At baseline and every other day. Method of measurement: Visual Analog Scale.;Severity and quality of pain. Timepoint: At baseline and every other day. Method of measurement: Neuropathic Pain Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dose of other analgesic drugs. Timepoint: At the end of the study. Method of measurement: Recording the dose of other analgesics.;Adverse effects. Timepoint: During the study. Method of measurement: Patient report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Najafi
Kerman University of Medical Sciences
Outcome results
None listed