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The effect of olive extract on arthrosis of the knee

The effect of hydroalcoholic extract of olive leaf on osteoarthritis of the knee and daily functioning of the elderly

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170514033961N7
Enrollment
120
Registered
2021-01-23
Start date
2021-01-03
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthrit. Osteoarthritis of knee

Interventions

Intervention group 1: For intervention in this group, high quality olive leaf extract ointment of coronaci species prepared by Danakasia company is provided to the research samples and they will be tr

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: The individual's desire to participate in the study Being 60-80 years old Diagnosis of primary osteoarthritis of the knee Participating in the study based on the diagnosis of an orthopedic specialist (based on the description of clinical symptoms, physical examination, radiographic criteria and diagnostic properties related to the disease) Have Osteoarthritis Grade 1-3 Based on American College of Rheumatology Classification Criteria Having moderate pain according to visual analog criteria (4-7) No dependence on others in performing daily activitiesFailure to perform physiotherapy and surgery in the last 12 months No intra-articular injection of steroids in the last 6 months Having a body mass index of less than 30 Have a performance score above 34 No neurological diseases associated with movement and balance disorders

Exclusion criteria

Exclusion criteria: Creating acute medical conditions The death of the elderly at the time of study Reluctance to continue participating in the study Sensitivity to olives Existence of cognitive disorders Secondary osteoarthritis in rheumatologydiseases (such as rheumatoid arthritis, gout, infectious arthritis, metabolic arthritis, traumatic arthritis)

Design outcomes

Primary

MeasureTime frame
Knee pain score. Timepoint: The beginning of the study, the second, fourth, sixth, eighth week. Method of measurement: Visual Analog Scale,.;Joint dryness score. Timepoint: The beginning of the study, the second, fourth, sixth, eighth week. Method of measurement: Osteoarthritis Index of West Ontario University and McMaster.;Psychological performance score. Timepoint: The beginning of the study, the second, fourth, sixth, eighth week. Method of measurement: Osteoarthritis Index of West Ontario University and McMaster.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsaki mandana

Khoram-Abad University of Medical Sciences

mandana-saki@yahoo.com+98 66 3331 6465

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026