Addicted patients with opioid dependence. Mental and behavioural disorders due to use of opioids
Conditions
Interventions
Intervention 1: Biography of included patients is registered and distributed in one of the study groups, and to each group of these patients, different doses of 4 mg and 8 mg of andestron are injected
Treatment - Drugs
Biography of included patients is registered and distributed in one of the study groups, and to each group of these patients, different doses of 4 mg and 8 mg of andestron are injected intravenously 1
The control group received all the conditions for the treatment group with ondansetrone, except that they received a placebo containing 2 ml of distilled water, which is injected intravenously 15 minu
Sponsors
Pharmaceutical Research Center, Faculty of Pharmacy
Eligibility
Sex/Gender
Male
Age
19 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients addicted to opiates in the age range of 19-70 years and have fractures. Exclusion criteria:addicted patients who have multi-drug use together or surgery prolongation or induction and maintenance of anesthesia with other Protocol that fentanyl not included.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Withdrawal signs and pain. Timepoint: Up to 2h after ondansetron ijjection. Method of measurement: Observation.;Withdrawal signs and pain. Timepoint: Visual analogue scale. Method of measurement: Up to 2h after injection of ondansetron. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Up to 2h after ondansetron injection. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Reza Rahimi
Kerman Faculty of Pharmacy
Outcome results
None listed