Brucellosis. Brucellosis
Conditions
Interventions
Intervention 1: Intervention group: Probiotic capsule (Zisttakhmir Co., Iran) including 2×109 Lactobacillus acidophilus, 2×109 Bifidobacterium bifidum, 2×109 Lactobacillus reuteri, 2×109 Lactobacillus
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
8 Years to 15 Years
Inclusion criteria
Inclusion criteria: Children diagnosed with brucellosis Children aged 8-15 years
Exclusion criteria
Exclusion criteria: Taking any antioxidant and/or anti-inflammatory supplements within 3 months prior to the enrollment. Children diagnosed with acquired immunosuppressive disease Patients who are receiving any immunosuppressive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum hs-CRP levels. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Elisa. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fever duration. Timepoint: After intervention. Method of measurement: Checklist.;Chills duration. Timepoint: After intervention. Method of measurement: Checklist.;Sweating duration. Timepoint: After intervention. Method of measurement: Checklist.;Musculoskeletal pain. Timepoint: After intervention. Method of measurement: Checklist.;Anorexia duration. Timepoint: After intervention. Method of measurement: Checklist.;Total antioxidant capacity. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Malondialdehyde. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry.;Glutathione. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Spectrophotometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Reza Sharif
Kashan University of Medical Sciences
Outcome results
None listed