Obesity Hypoventilation syndrome (OHS). Extreme obesity with alveolar hypoventilation
Conditions
Interventions
Intervention 1: Treatment with daily titrated positive airway pressure with Bipap or Cpap device manufactured by ResMed company for at least 4 hours in one day in a period of 12 weeks. Intervention 2:
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Obesity hypoventilation syndrome (OHS) patient Adult older than 18 Patients without COPD Patients without restrictive lung disease Patients without problems of chest wall BMI greater than 35 Paco2>45
Exclusion criteria
Exclusion criteria: Patients with known COPD Scoliosis Patients with known restrictive lung disease Patient younger than 18 congestive heart failure (EF<40%) Fev1/FVC< 70
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Co2 pressure (pco2). Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: By capnograph.;O2 saturation. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: By pulse oximeter.;Epworth Sleepiness Scale score. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: By Epworth Sleepiness Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactForoogh Soltaninejad
Esfahan University of Medical Sciences
Outcome results
None listed