Effect of adding neostigmine and fentanyl to bupivacaine in caudal analgesia

Comparison of the effect of neostigmine and fentanyl when added to bupivacaine in caudal analgesia in inguinal herniorrhaphy for children aged between 1 to 6 years double-blind clinical study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017051126866N3

Enrollment

140

Registered

2017-06-11

Start date

2017-05-31

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

local aneasthetics. Local anaesthetics

Interventions

Patients were assigned, using permuted block randomization method, into four groups of 35. Children in the first group received a caudal injection of 0.5 ml/kg bupivacaine 0.25% plus fentanyl 1µ/kg. T

Treatment - Drugs

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: A total of 140 children, aged 1-6 year and ASA physical status I, who were scheduled to elective herniorrhaphy, were enrolled. Exclusion criteria were sacral area infection, history of allergic reactions to local anesthetics, bleeding tendency, neurological or spinal disease and lack of parent consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: evry 15 minutes after intervention. Method of measurement: Wong Baker Scale.	—

Secondary

Measure	Time frame
Blood Pressure. Timepoint: Every 15 minutes aftere intervention. Method of measurement: mm Hg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Isfahan University Of Medical Sceince

shafa_amir@yahoo.comamir_shafa@med.mui.ac.ir+98 31 3773 5509

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026