Patients with chronic periodontitis. Chronic periodontitis
Conditions
Interventions
Intervention 1: Intervention group:
Scaling , root planning,
Anaheal Bromelain prescription four times a day for eight weeks. Intervention 2: Control group: Scaling ,root planning,
placebo prescriptio
Treatment - Drugs
Placebo
Intervention group:
Scaling , root planning,
Anaheal Bromelain prescription four times a day for eight weeks
Control group: Scaling ,root planning,
placebo prescription four times a day
Sponsors
Department of Periodontics of Dental Faculty of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients who suffer from moderate chronic periodontitis with clinical attachment loss (CAL) of 3 to 4 millimeters who were systemically healthy. Exclusion criteria : Sensitivity to the medication (patients with sensitivity to pineapple, celery, carrot and fennel may also have sensitivity to Bromelain),History of cardiac diseases, Pregnant women, Gastrointestinal diseases such as peptic ulcer, Renal or Hepatic Diseases, coagulated anomalies such as hemophilia, Systemic lupus erythematous, Any history of periodontal treatment (scaling, root planning or surgery) at the past six months, Alcohol, cigarette or drug consumption, Concurrent Anti-coagulant or thrombolytic therapy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CAL (clinical attachment level). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: measurement of the distance between the stent margin to the sulcus base by means of a periodontal probe. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque. Timepoint: Before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: by disclosing agent with visual scale.;Bleeding on probing(BOP). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: bleeding in 15 seconds after gentle probing by periodontal probe.;Probing depth(PD). Timepoint: Before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: The distance between the mucosal margin and the sulcus base by periodontal probe in millimeters.;Gingival index(GI). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: observation of index score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Zarandi
Department of Periodontics of Dental Faculty of Tabriz University of Medical Sciences
Outcome results
None listed