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Comparison of two treatment method in children with primary nocturnal enuresis

Comprasion of additive effect of solifenacin with tolterodine to desmopressin in treatment of children with primary nocturnal enuresis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170509033894N3
Enrollment
40
Registered
2018-01-31
Start date
2017-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nocturnal enuresis. Nonorganic enuresis

Interventions

Intervention 1: Intra nasal Desmopressin 1 puff/Qhs plus Tolterodine 1mg daily during 6 month. Intervention 2: Intra nasal Desmopressin 1 puff/Qhs plus solifenacin 5 mg daily during 6 month.
Treatment - Drugs
Intra nasal Desmopressin 1 puff/Qhs plus Tolterodine 1mg daily during 6 month
Intra nasal Desmopressin 1 puff/Qhs plus solifenacin 5 mg daily during 6 month

Sponsors

Vice Chancellor for Research and Technology of Ahvaz Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 15 Years

Inclusion criteria

Inclusion criteria: children with primary nucturnal enurises

Exclusion criteria

Exclusion criteria: patients with neurogenic bladder CNS disorders urine-concentrating defects

Design outcomes

Primary

MeasureTime frame
Response to treatment. Timepoint: Monthly regarding during 6 months. Method of measurement: According things that their parents and children say, patients will be classified to full response (complete dry), good response (90 to 99% reduction in wet nights), and partial response (50 to 90% reduction).

Secondary

MeasureTime frame
Abdominal pain. Timepoint: Monthly during 6 months. Method of measurement: Clinical symptoms.;Vomiting. Timepoint: Monthly during 6 months. Method of measurement: Clinical symptoms.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Parvin Mosavi Ghanavati

Ahvaz University of Medical Sciences

sp.mg90@yahoo.com+98 61 3221 6104

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026