Effect of diclofenac eye drop and Bevacizumab and Triamcinolone in preventing part of the retina edema

Effect of intravitreal injection of Bevacizumab and subtenon injection of Triamcinolone and topical diclofenac eye drop in preventing the incidence of diabetic macular edema after phaco with intraocular lens implementing

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017050833875N1

Enrollment

Registered

2017-06-30

Start date

2017-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic retinopathy. Diabetic retinopathy

Interventions

Intervention 1: Group I (intervention group): Prescription 1.25 milligram of intravitreal Bevacizumab injection at the end of the surgery. Intervention 2: Group II (intervention group): Prescription 4

Prevention

Group II (intervention group): Prescription 4 milligram of subtenon Triamcinolone injection at the end of the surgery.

Group III (control group): Prescription topical diclofenac eye drop every 8 hours until 4 weeks after surgery.

Group I (intervention group): Prescription 1.25 milligram of intravitreal Bevacizumab injection at the end of the surgery.

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Diabetic patients with cataract and without diabetic macular edema; Nonproliferation diabetic retinopathy. Exclusion Criteria: Glaucoma; Eye trauma; Laser therapy 12 months prior to cataract surgery; Any history of eye surgery 6 months ago.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Macular thickness. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: spectral domain optical coherence tomography (SD-OCT).;Visual acuity. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: Snellen chart.;Intraocular pressure. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: Goldman tonometer.	—

Measure

Time frame

Macular thickness. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: spectral domain optical coherence tomography (SD-OCT).;Visual acuity. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: Snellen chart.;Intraocular pressure. Timepoint: Before the surgery and one month and three months after surgery. Method of measurement: Goldman tonometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAram Mohamad Jafari

Ahvaz Jundishapur University of Medical Sciences

arammohamadjafary@yahoo.com+98 61 3222 2922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026