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Effect of axillary perineural injection of dexmedetomidine on hemodynamic changes during the surgical operation and post-operative pain in patients udergoing orthopedic upper extremity surgery

Effect of axillary perineural injection of dexmedetomidine on hemodynamic changes during the surgical operation and post-operative pain in patients udergoing orthopedic upper extremity surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017050833860N1
Enrollment
60
Registered
2017-11-01
Start date
2017-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of forearm.

Interventions

Intervention 1: ]intervention group: 100 µg Dexmedmotidine infusion in the auxiliary and pre- neural region.Induction was carried out by using 5mg/kg Sodium thiopental and 0.5 mg/kg atracurium. Interv
Treatment - Drugs
]intervention group: 100 µg Dexmedmotidine infusion in the auxiliary and pre- neural region.Induction was carried out by using 5mg/kg Sodium thiopental and 0.5 mg/kg atracurium.
Control group: No injections was used.Induction was carried out by using 5mg/kg Sodium thiopental and 0.5 mg/kg atracurium.

Sponsors

Vice chancellor for research, Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age 18-65, ASA 1, 2, Fracture of the forearm and hands bones, BMI = 35 and Patient consent form for study participation. exclusion criteria:Pregnancy, addiction, history of use of agonist or 2a adrenergic antagonist's drugs, coagulation disorders, hypersensitivity to intraoperative drugs and prolonged surgery for more than 120 minutes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: Before induction and every 15 minutes during surgery. Method of measurement: Monitoring device.;Diastolic blood pressure. Timepoint: Before induction and every 15 minutes during surgery. Method of measurement: Monitoring device.;Heart rate. Timepoint: Before induction and every 15 minutes during surgery. Method of measurement: Monitoring device.;Postoperative pain. Timepoint: At recovery, 3, 6, 12 and 24 hours after surgery. Method of measurement: visual analogue scale.;Drug use. Timepoint: In the recovery and the first 24 hours after surgery. Method of measurement: Injection dose based on mg.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mehdi Rajabi

Kashan University of Medical Sciences

rajabimmh@gmail.com+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026