Proliferation of human spermatogonia in non-obstructive azoospermia

Effects of isolation and proliferation of human spermatogonia in treatment of non-obstructive azoospermia infertility

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017050829027N4

Enrollment

Registered

2017-06-03

Start date

2017-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male Infertility. Azoospermia

Interventions

Sertoli cells and spermatogonial stem cells are isolated from testicular tissue in infertile men with non-obstructive azoospermia. Spermatogonial stem cells is cultured for three weeks. Transplantatio

Treatment - Other

Eligibility

Sex/Gender

Male

Age

22 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: male infertility; age between 22-60; non-obstructive azoosperima; maturation arrest in testicular biopsy; married men; consent inform Exclusion criteria: history of testicular surgery; recent sexual transmitted infection; anatomical abnormalities of testis; cancers

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Spermatogenesis. Timepoint: 3 months. Method of measurement: Sperm analysis.	—

Secondary

Measure	Time frame
Fertility. Timepoint: 12 months. Method of measurement: Positive serum pregnancy test of his wife.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Noori

Geneocell group

masoume.nouri2002@gmail.com+98 21 8819 6540

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026