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Evaluation of the effect of omega 3 fatty acid in patients with hashimoto thyroiditis

Evaluation of the effect of omega 3 fatty acid (fish oil) on serum levels of inflammatory factors in patients with hashimoto thyroiditis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017050629508N6
Enrollment
60
Registered
2017-07-06
Start date
2016-09-24
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hashimoto disease. Autoimmune thyroiditis

Interventions

Intervention 1: Intervention group: received omega-3 supplement for 8 weeks 3 grams per day in three divided doses (one pill three times a day after meals) containing 180mg eicosapentaenoic acid and 1
Placebo
Intervention group: received omega-3 supplement for 8 weeks 3 grams per day in three divided doses (one pill three times a day after meals) containing 180mg eicosapentaenoic acid and 120mg docosahexae
Placebo group: took placebo pills containing edible paraffin 3 times in a day for 8 weeks

Sponsors

by my own
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
17 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Hashimoto patients over 18 years. Exclusion criteria: patients with rheumatoid arthritis; celiac disease; pernicious anemia; Systematic lupus erythematous and other autoimmune disease and other acute or chronic infections disease; postmenopausal women; pregnant and lactating women; taking drugs such as warfarin; aspirin; gamma interferon; smoking; using contraceptive drugs; Seasonal allergies; allergy to the fish or oil fish; eating fish over twice in week.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
TNF-a (tumor necrosis factor alpha). Timepoint: before and 8 week after intervention. Method of measurement: laboratory kit.;ESR (erythrocyte sedimentation rate). Timepoint: before and 8 week after intervention. Method of measurement: laboratory kit.;Hs_CRP (high-sensitivity C-reactive protein). Timepoint: before and 8 week after intervention. Method of measurement: laboratory kit.

Secondary

MeasureTime frame
24 hour recall. Timepoint: before and 8 week after intervention. Method of measurement: 24 hour recall questioniare.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Rasoul Zarrin

Urmia University of Medical Science

Rasoul.zarrin@uqconnect.edu.au, wwzarrin@yahoo.com+98 44 3346 9935

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026