The effect sedation level on weaning of mechanical ventilation

The effect of controlled sedation based Richmond tool on clinical outcomes in mechanically ventilated patients admitted to intensive care units

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017050517693N2

Enrollment

Registered

2017-05-24

Start date

2017-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mechanical ventilation duration. Other complications of procedures, not elsewhere classified , Other specified medical care

Interventions

Intervention 1: Intervention group: Mechanically ventilated patients receive the amount of sedative based on Richmond scale measured every hour the sedation level. Intervention 2: Control group: Me

Intervention group: Mechanically ventilated patients receive the amount of sedative based on Richmond scale measured every hour the sedation level

Control group: Mechanically ventilated patients receive routinely the amount of sedative without used agitation sedation scales

Eligibility

Sex/Gender

All

Age

17 Years to 17 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients undergoing coronary artery bypass graft (CABG); From ages 30 to 70 years old; Need for mechanical ventilation for less than 24 hours after the operation; The number of one to four arterial grafts without the need to Endarectomy; Lack of hearing and vision problems or difficulty in understanding the language of Persian Exclusion criteria: Cardiac and respiratory arrest after surgery; The need for re-operation due to abnormal bleeding

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sedation level. Timepoint: intervention time. Method of measurement: richmond scale.;Pain. Timepoint: intervention time. Method of measurement: COPT scale.;Mechanical ventilation duration. Timepoint: intervention time. Method of measurement: hour.;The amount of using of sedative. Timepoint: intervention time. Method of measurement: mg,mcigram/h , based on a sedation.	—

Secondary

Measure	Time frame
Length of stay in Hospital. Timepoint: discharge or dead. Method of measurement: day.;Length of stay in ICU. Timepoint: discharge of ICU. Method of measurement: hour.;Median arterial pressure. Timepoint: intervention time. Method of measurement: mmHG with manitor.;Body mass index. Timepoint: before intervention. Method of measurement: weight by meters squared.;Pulse pressure. Timepoint: intervention time. Method of measurement: mmHG with manitor, difference between SBPand DBP.;Pulse rate. Timepoint: intervention time. Method of measurement: bpm with monitor.;O2 saturation. Timepoint: intervention time. Method of measurement: percentage.	—

Measure

Time frame

Length of stay in Hospital. Timepoint: discharge or dead. Method of measurement: day.;Length of stay in ICU. Timepoint: discharge of ICU. Method of measurement: hour.;Median arterial pressure. Timepoint: intervention time. Method of measurement: mmHG with manitor.;Body mass index. Timepoint: before intervention. Method of measurement: weight by meters squared.;Pulse pressure. Timepoint: intervention time. Method of measurement: mmHG with manitor, difference between SBPand DBP.;Pulse rate. Timepoint: intervention time. Method of measurement: bpm with monitor.;O2 saturation. Timepoint: intervention time. Method of measurement: percentage.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Yeganeh

Guilan University of Medical Sciences, Vice chancellor for research

yeganeh@gums.ac.ir+98 13 3336 2772

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026