Chronic Rhinosinusitis. Chronic Rhinitis, Chronic Sinusitis
Conditions
Interventions
Intervention 1: Intervention group: Endoscopic Sinus Surgery. Intervention 2: Control group: nasal irrigation of normal saline (4 times daily) and nasal corticosteroids fluticasone (one puff daily) fo
Treatment - Surgery
Treatment - Drugs
Intervention group: Endoscopic Sinus Surgery
Control group: nasal irrigation of normal saline (4 times daily) and nasal corticosteroids fluticasone (one puff daily) for three months
Sponsors
Vice Chancellor for Research, Baqiyatallah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Patients between 18 and 65 years of age; no response to standard medical treatment with nasal irrigation by normal saline (4 times daily), nasal corticosteroid Fluticasone (one puff daily) and antibiotic therapy by Cefixime (400 mg daily) for 4 weeks Exclusion criteria: Head trauma; Smoking; prior other treatments
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Olfactory threshold. Timepoint: Before, one month and three months after interventin. Method of measurement: Smell Threshold Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug Complications. Timepoint: During study. Method of measurement: Patients' complaint.;Surgical Complications. Timepoint: After surgery. Method of measurement: Examination and patients' complaints. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMorteza Izadi
Baqiyatallah University of Medical Sciences
Outcome results
None listed