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The effects of curcumin on Attention-Deficit/Hyperactivity Disorder (ADHD) patients

A clinical trial to compare the effects of curcumin with placebo on Attention-Deficit/Hyperactivity Disorder (ADHD) patients undergoing Ritalin treatment

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017050433810N1
Enrollment
70
Registered
2017-05-28
Start date
2017-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention-Deficit/Hyperactivity Disorder (ADHD). Disturbance of activity and attention

Interventions

Intervention 1: Control group: Children and teenagers with Attention-Deficit/Hyperactivity Disorder (ADHD) undergoing Ritalin treatment (0.1-3 mg) received 80 mg of placebo (similar components of curc
Treatment - Drugs
Control group: Children and teenagers with Attention-Deficit/Hyperactivity Disorder (ADHD) undergoing Ritalin treatment (0.1-3 mg) received 80 mg of placebo (similar components of curcumin capsules) t
Intervention group: Children and teenagers with Attention-Deficit/Hyperactivity Disorder (ADHD) undergoing Ritalin treatment (0.1-3 mg) received 80 mg of curcumin (Sina Drug) twice a day.

Sponsors

Vice Chancellor for Research, Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 15 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Aged between 7 and 15 years; diagnosis Attention-Deficit/Hyperactivity Disorder (ADHD) based on DSM-V-TR criteria; lack of mental retardation (MR), epilepsy, pervasive developmental disorder, schizophrenia, mania episode, anxiety disorders, bipolar disorder, special ability and learning disorders, and hyperactivity disorder due to organic brain syndrome (OBS) or drug reactions. Exclusion criteria: Liver and renal failure; thyroid disorder; allergy to curcumin; chronic inflammatory diseases; use of anti-inflammatory and antioxidant drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Evaluation the effectiveness of clinical outcomes including learn, impulsivity, anxiety, hyperactivity and conduct disorder (CD) score. Timepoint: before, 4 and 8 weeks after intervention. Method of measurement: Base on questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzea Ranghian

Mashhad University of Medical Sciences

rangianm931@mums.ac.ir+98 51 3728 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026