Non-alcoholic fatty liver. Nonalcoholic steatohepatitis
Conditions
Interventions
Intervention 1: Intervention group: lifestyle modification and Vitamin E 400IU/day for 3 months. Intervention 2: Intervention group: lifestyle modification and pioglitazone 15 mg/day for 3 months. Int
Treatment - Drugs
Intervention group: lifestyle modification and Vitamin E 400IU/day for 3 months
Intervention group: lifestyle modification and pioglitazone 15 mg/day for 3 months
Control group: lifestyle modification and placebo for 3 months
Sponsors
Vice chancellor for research, Shiraz University Of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Patients with NAFLD confirmed by performing liver sonography and increased levels of liver enzymes AST and ALT. Exclusion Criteria: History of alcohol consumption; diabetes; chronic liver disease; use of drugs such as statin, fibrate.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function test. Timepoint: Before intervention - 3 months after intervention. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index. Timepoint: Before intervention - 3 months after intervention. Method of measurement: By BMI Formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNiloofar Hadadi
International branch_Shiraz University of Medical Sciences
Outcome results
None listed