Condition 1: Burn. Condition 2: Burn. Condition 3: Burn. Condition 4: Burn. Condition 5: Burn. Condition 6: Burn. Burn and corrosion of head and neck Burn and corrosion of shoulder and upper limb, except wrist and hand Burn and corrosion of trunk Burn and corrosion of wrist and hand Burn and corrosion of hip and lower limb, except ankle and foot Burn and corrosion of ankle and foot
Conditions
Interventions
Intervention 1: In intervention group
Tab pantoxyfylline 400 mg every 8 hours for a week. Intervention 2: In control group
Placebo with same shape and null substance.
Treatment - Drugs
In intervention group
Tab pantoxyfylline 400 mg every 8 hours for a week
In control group
Placebo with same shape and null substance
Sponsors
Vice Chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria : Burn above 40% of body surface; Admission in maximum of an hour. Exclusion criteria : Known comorbidities such as renal and heart faliure and respiratory disorders; Any other type of trauma; Disagree of patient or first degree relatives for participating in study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of IL-1and IL-6. Timepoint: At admission time and days 3,5 and 7. Method of measurement: Measuring serum levels.;Days of admission to ICU. Timepoint: From admission to discharge. Method of measurement: Registered by days and hours.;Death or discharge. Timepoint: From admission to discharge or death. Method of measurement: Registered outcome. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir hossein ladan
Tabriz university of medical sciences
Outcome results
None listed