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Effect of probiotic supplementation on oxidative stress marker

Comparison of the effects of probiotic supplementation and omega 3 on oxidative stress marker in healthy children and adolescents exposed to air pollutants: A Randomized, Double-Blind, Placebo-Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170501033747N3
Enrollment
100
Registered
2020-04-19
Start date
2020-09-22
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects expose to air pollution. Contact with and (suspected) exposure to air pollution

Interventions

Intervention 1: The intervention group will consume 1 FamiLact capsules (zist takhmir company, Tehran, Iran) daily for 8 weeks. FamiLact ® is a synbiotic (probiotic + prebiotic) formulation and conta

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 16 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study Healthy subject without any chronic physiological disorders and endocrine diseases Subjects should not take any antioxidant supplements or probiotic products during the study and in the past month Subjects that live in the pollutant areas

Exclusion criteria

Exclusion criteria: Unwillingness to continue study Use of antioxidant supplements other than supplements selected during the study Gastrointestinal problems or sensitivity to the supplement Failure to follow the intervention of the study

Design outcomes

Primary

MeasureTime frame
Plasma Malondialdehyde. Timepoint: Before the intervention and after the intervention. Method of measurement: ELISA Kit.

Secondary

MeasureTime frame
Height. Timepoint: Before the intervention and after the intervention. Method of measurement: Meter.;Weight. Timepoint: Before the intervention and after the intervention. Method of measurement: Scale.;Waist circumference. Timepoint: Before the intervention and after the intervention. Method of measurement: Meter.;Body Mass Index. Timepoint: Before the intervention and after the intervention. Method of measurement: weight (Kg)/ Squared meters.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMotahar Heidari-Beni

Esfahan University of Medical Sciences

heidari.motahar@gmail.com+98 31 3792 5284

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026