Essential hypertension. Hypertensive diseases
Conditions
Interventions
Intervention 1: The intervention group: olive leaf extract as 250 mg tablet, orally ,twice a day for 12 weeks. Intervention 2: The control group: Cellulose as 250 mg tablet as placebo, orally twice a
Treatment - Drugs
Placebo
The intervention group: olive leaf extract as 250 mg tablet, orally ,twice a day for 12 weeks.
The control group: Cellulose as 250 mg tablet as placebo, orally twice a day for 12 weeks.
Sponsors
Vice Chancellor for research of Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: subjects with systolic blood pressure (SBP) above 140 mmHg or diastolic blood pressure (DBP) above 90 mmHg. Exclusion criteria: patients who do not want to cooperate; hypertensive patients who have others complications such as: kidney disease? neuropathy and retinopathy; patients with hypo and/or hyperthyroidism are excluded from this study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure. Timepoint: Before and after intervention. Method of measurement: based on mmHg using sphigmomanometer.;MDA. Timepoint: Before and after intervention. Method of measurement: Elisa.;Total antioxidant capacity. Timepoint: Before and after intervention. Method of measurement: spectrophotometeric.;Lipid profiles. Timepoint: Before and after intervention. Method of measurement: spectrophotometeric. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Seyyed Mehdi Mirhashemi
Qazvin University of Medical Sciences
Outcome results
None listed