The Combined Effect of black cohosh, soybean, arctium lappa L and vitex agnus- castus extracts On menopause

The Combined Effect of black cohosh, soybean, arctium lappa L and vitex agnus- castus extracts on clinical symptoms, biomarkers of oxidative stress biomarkers and inflammation among menopausal women

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170430033730N8

Enrollment

Registered

2021-03-11

Start date

2021-02-13

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menopause. Menopausal and other perimenopausal disorders

Interventions

Intervention 1: Intervention group: will receive two capsules of 550 mg of combined extract(Black cohosh, Soybean, Sweet potato, Greater burdock, Vitex) twice daily for 8 weeks. The capsules are ma

Eligibility

Sex/Gender

Female

Age

45 Years to 55 Years

Inclusion criteria

Inclusion criteria: Having menopausal symptoms

Exclusion criteria

Exclusion criteria: patients who do not want to cooperate People who smoke People who drink alcohol Patients with gastrointestinal disorders Diabetic Patients Thyroid disease, breast and ovarian cancer, liver and neurological disorders, high blood pressure, taking anticoagulants

Design outcomes

Primary

Measure	Time frame
Clinical symptoms. Timepoint: Beginning and end of the study. Method of measurement: Quality of life questionnaire for menopausal women.	—

Secondary

Measure	Time frame
Glutathione. Timepoint: Beginning and end of the study. Method of measurement: Spectrophotometry.;MDA. Timepoint: Beginning and end of the study. Method of measurement: Spectrophotometry.;TNF-a. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;IL-8. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;Gonadotropins. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;E2. Timepoint: Beginning and end of the study. Method of measurement: ELISA.	—

Measure

Time frame

Glutathione. Timepoint: Beginning and end of the study. Method of measurement: Spectrophotometry.;MDA. Timepoint: Beginning and end of the study. Method of measurement: Spectrophotometry.;TNF-a. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;IL-8. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;Gonadotropins. Timepoint: Beginning and end of the study. Method of measurement: ELISA.;E2. Timepoint: Beginning and end of the study. Method of measurement: ELISA.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Mehdi Mirhashemi

Qazvin University of Medical Sciences

mirhashemism@gmail.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026