Recurrent aphthous stomatitis. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: Intervention group: Patients will be given 3 mucoadhesives containing 10 mg of atorvastatin daily for 10 days to use in the morning, noon and night.This mucoadhesive is made in the lab
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients with recurrent aphthous stomatitis showing aphthous lesions in the lips and buccal mucosa No systemic disease Do not take immunosuppressive drugs for the past month Do not use dentures Do not take antibiotics
Exclusion criteria
Exclusion criteria: Pregnant patients People who are not able to use mucoadhesive People with syndromes in which aphthous ulcers are manifestations (Behjat syndrome) the smokers People with autoimmune mucocutaneus lesions Patients with liver failure, myopathy and muscle problems Patients with allergies, hives and itchy skin and mucous membranes People who can not stay in the study due to personal or social reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The size of the erythematous halo around the aphthous lesion. Timepoint: 0 (Before intervention) and 3, 5 and 7 days after aphthous lesion. Method of measurement: Metal caliber.;Patients' pain intensity. Timepoint: 0 (Before intervention) and 3, 5 and 7 days after aphthous lesion. Method of measurement: Visual Analog Scale (universal Pain Assessment Tool). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaede Salehi Sarookolaei
Mazandaran University of Medical Sciences
Outcome results
None listed