Osteoarthritis. Arthrosis, unspecified
Conditions
Interventions
Intervention 1: zingiber zerumbet pomade, Knee local use. Dosage 1 grams per use 4 times a day. Intervention 2: Plus control group: diclofenac gel group. Knee local
use. Dosage 1 grams per use4 times
Treatment - Drugs
zingiber zerumbet pomade, Knee local use. Dosage 1 grams per use 4 times a day.
Plus control group: diclofenac gel group. Knee local
use. Dosage 1 grams per use4 times a day.
Sponsors
Immunology Research Center of Shahed University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Out-patients who suffer osteoarthritis based on clinical criteria of ACR
Exclusion criteria
Exclusion criteria: Those who need more than 2 grams of acetaminophen daily Those who need to use other oral or intravenous analgesic Sensitivity to study drugs Patients with Secondary osteoarthritis caused by rheumatic diseases such as rheumatoid arthritis Pregnancy Joint Replacement Concomitant use of glucosamine and chondrotin sulfate Knee corticosteroid injection in the past 3 months Oral or topical use of Corticosteroid in 14 past days Other Articular corticosteroid injection in the past 1 months Mussle corticosteroid injection in the past 1months Skin Diseases in Knee Radiculopathy and Neuropathy Alcohol addicted, Drug Abuse Patients with active Renal, Liver, and Peptic Ulcer Diseases Age under 30 or over 80 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire.;Physical Function. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire.;Stiffness. Timepoint: Before the intervention, the end of the second week and the end of the fourth week after the start of the intervention. Method of measurement: The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin 1. Timepoint: Before the intervention and the end of the fourth week after the start of the intervention. Method of measurement: Venous blood sample.;Interleukin 6. Timepoint: Before the intervention and the end of the fourth week after the start of the intervention. Method of measurement: Venous blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contacthasan kiani Ahmadabadi
Shahed University
Outcome results
None listed