The effect of diet on diabetes management

Comparison of the effect of high protein versus high carbohydrate intake at evening meal on glycemic control, lipid profile and oxidative stress in patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017042733666N1

Enrollment

Registered

2017-06-30

Start date

2017-07-01

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Intervention group: A 10-week diet with 40-45% of daily carbohydrate intake at evening meal and bedtime snack. Intervention 2: Intervention group: A 10-week diet with 40-45% of daily p

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Having type 2 diabetes mellitus according to American Diabetes Association criteria Diabetes duration of 1-15 years Age range of 30-65 years old Hemoglobin A1c (HbA1c) less than or equal to 8% Body mass index (BMI) 22- 35 kilograms per square meter Weight maintenance (± 3 kg) during past 3 month Stable medications during at least past two month Willingness to participate in study

Exclusion criteria

Exclusion criteria: Not taking insulin or a glucosidase inhibitors Not having heart, liver, kidney, thyroid, gastrointestinal and respiratory disorders or malignancies Not consuming alcohol Not being on special diets like gluten free or vegan Not being pregnant or lactating

Design outcomes

Primary

Measure	Time frame
Hemoglobin A1c. Timepoint: The begining and the end of the stuy. Method of measurement: In percent by using the assay kit.	—

Secondary

Measure	Time frame
Serum malondialdehyde. Timepoint: The begining and the end of the study. Method of measurement: In micromolar by using the assay kit.;Anthropometric measurements (body weight and waist circumference). Timepoint: The begining, middle and the end of the study. Method of measurement: By weighting scale with accuracy of 0.1 kg and measuring tape with accuracy of 0.1 cm.;Lipid profile (Triglyceride, Total cholestrol, Low density lipoprotein cholestrol, High density lipoprotein cholestrol). Timepoint: The begining and the end of the study. Method of measurement: In milligram per deciliter by using the assay kit.;Fasting serum insulin. Timepoint: The begining and the end of the study. Method of measurement: In picomole per liter by using the assay kit.;Fasting serum glucose. Timepoint: The begining of the study, the end of weeks 2 and 5, the end of the study. Method of measurement: In milligram per deciliter by using the assay kit.	—

Measure

Time frame

Serum malondialdehyde. Timepoint: The begining and the end of the study. Method of measurement: In micromolar by using the assay kit.;Anthropometric measurements (body weight and waist circumference). Timepoint: The begining, middle and the end of the study. Method of measurement: By weighting scale with accuracy of 0.1 kg and measuring tape with accuracy of 0.1 cm.;Lipid profile (Triglyceride, Total cholestrol, Low density lipoprotein cholestrol, High density lipoprotein cholestrol). Timepoint: The begining and the end of the study. Method of measurement: In milligram per deciliter by using the assay kit.;Fasting serum insulin. Timepoint: The begining and the end of the study. Method of measurement: In picomole per liter by using the assay kit.;Fasting serum glucose. Timepoint: The begining of the study, the end of weeks 2 and 5, the end of the study. Method of measurement: In milligram per deciliter by using the assay kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Nouripour

Shiraz University of Medical Sciences

nouripourf@sums.ac.ir+98 71 3725 1007

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026