Evaluation of the effects of branched chain amino acid oral supplements on inflammatory markers and nutritional scales of hemodialysis patients

the evaluation of the effects of Branched chain amino acid supplements on inflammatory markers and nutritional scales of hemodialysis patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170427033665N3

Enrollment

150

Registered

2018-03-11

Start date

2017-08-23

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: End stage renal disease. Condition 2: nutrition in patients with renal failure. chronic renal failure stage5 NUTRITION

Interventions

Intervention 1: oral branched chain amino acids supplementation. Intervention 2: placebo.

Eligibility

Sex/Gender

All

Age

17 Years to 59 Years

Inclusion criteria

Inclusion criteria: patients who are undergoing Hemodialysis for at least three months

Exclusion criteria

Exclusion criteria: cerebrovascular accident advanced heart failure malignancy liver cirrhosis chronic infection sever psychological disease chronic obstructive pulmonary disease hospitalization in recent 3 months using other nutritional supplements

Design outcomes

Primary

Measure	Time frame
Nutritional scales score. Timepoint: before and 3 months after intervention. Method of measurement: questioner and physical examination.;Body fat percent. Timepoint: before and 3 months after intervention. Method of measurement: caliper.;Body Mass Index. Timepoint: before and 3 months after intervention. Method of measurement: meter and acale.;Lean body mass. Timepoint: before and 3 months after intervention. Method of measurement: body composition stat.;Interlukin-6 level. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Hs-CRP level. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Transferin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Albumin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Ferritin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Hemoglobin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.	—

Measure

Time frame

Nutritional scales score. Timepoint: before and 3 months after intervention. Method of measurement: questioner and physical examination.;Body fat percent. Timepoint: before and 3 months after intervention. Method of measurement: caliper.;Body Mass Index. Timepoint: before and 3 months after intervention. Method of measurement: meter and acale.;Lean body mass. Timepoint: before and 3 months after intervention. Method of measurement: body composition stat.;Interlukin-6 level. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Hs-CRP level. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Transferin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Albumin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Ferritin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.;Hemoglobin. Timepoint: before and 3 months after intervention. Method of measurement: blood sampling.

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Secondary

Measure	Time frame
Drug complication. Timepoint: before and every week during and 6 months after intervention. Method of measurement: questioner.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Musavi Mahdiabadi

Kerman University of Medical Sciences

f_musavi_59@yahoo.com+98 34 3243 8920

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026