Comparison the effect of rectal and oral misoprostol in First Trimester of Pregnancy Induced Abortion

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017042533635N1

Enrollment

140

Registered

2017-06-21

Start date

2017-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

induced abortion. other obstetric conditions-not elsewhere classified

Interventions

Intervention 1: Misoprostol tab 200 microgram with primary dose of 600 and two dose of 300 per 6 hours in first group by rectally. Intervention 2: Misoprostol tab 200 microgram with primary dose of 6

Treatment - Drugs

Misoprostol tab 200 microgram with primary dose of 600 and two dose of 300 per 6 hours in first group by rectally

Misoprostol tab 200 microgram with primary dose of 600 and two dose of 300 per 6 hours in second group by orally

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Including factors: singleton pregnancy ,gravid 2 -4,without cervical dilatation and bleeding or tissue passing,report of IUFD in two sonographys,gestational age below 14 w,BMI Between 19.8-26 kg/m2 Excluding factors:background diseases related with study such as overt DM,chronic Hypertension,SLE,fever or chorioamnionitis signs,using unusual drugs in pregnant women,addiction,...

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Complete abortion. Timepoint: during hospitalization. Method of measurement: uterine sonogeraphy.;Incomplete abortion. Timepoint: during hospitalization. Method of measurement: uterine sonogeraphy.;Cervical ripening. Timepoint: during hospitalization and in time of curettage. Method of measurement: passing the number 8 bugie.;Nausia. Timepoint: during hospitalization. Method of measurement: observation and patient expression.;Vomitting. Timepoint: during hospitalization. Method of measurement: observation.;Fever. Timepoint: during hospitalization. Method of measurement: body temperature > 38 c.;Time of drug effect. Timepoint: repetitive visit and patient expression. Method of measurement: observation and examination.	—

Measure

Time frame

Complete abortion. Timepoint: during hospitalization. Method of measurement: uterine sonogeraphy.;Incomplete abortion. Timepoint: during hospitalization. Method of measurement: uterine sonogeraphy.;Cervical ripening. Timepoint: during hospitalization and in time of curettage. Method of measurement: passing the number 8 bugie.;Nausia. Timepoint: during hospitalization. Method of measurement: observation and patient expression.;Vomitting. Timepoint: during hospitalization. Method of measurement: observation.;Fever. Timepoint: during hospitalization. Method of measurement: body temperature > 38 c.;Time of drug effect. Timepoint: repetitive visit and patient expression. Method of measurement: observation and examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contactmina khaje

zahedan university of medical sciences

nsakhavar@yahoo.co.uk+98 54 3329 5570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026