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Effect of supplementation in treatment of women with gestational diabetes

Clinical trial of the effect of magnesium supplementation compared with the placebo on gene expression related to insulin and lipid in women with gestational diabetes

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201704235623N111
Enrollment
40
Registered
2017-04-29
Start date
2017-03-07
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes. Diabetes mellitus in pregnancy, unspecified

Interventions

Intervention 1: Intervention group: Magnesium supplements (21st Century, Arizona, USA), 250 mg, daily, for 6 weeks orally. Intervention 2: Control group: Placebo capsule, daily for 6 weeks orally.

Sponsors

Vice chancellor for research, Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with gestational diabetes Aged 18 to 40 years

Exclusion criteria

Exclusion criteria: Taking magnesium supplements within the past 3 months Needing to insulin therapy during the intervention Pre-eclampsia Eclampsia Hypo and hyperthyroidism Smokers

Design outcomes

Primary

MeasureTime frame
Expressed levels of PPAR-?. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: PCR.;Expressed levels of GLUT-1. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: PCR.

Secondary

MeasureTime frame
Expressed levels of LDLR gene. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: PCR.;Expressed levels of Lp(a) gene. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: PCR.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehri Jamilian

Arak University of Medical Sciences

mjamilian@yahoo.com+98 86 8670 2503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026