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Control of shivering after surgery in addicted patients

Effect of Preemptive Clonidnine versus Pethidine and Ketamine on Postoperative Shivering in addicted patients during Spinal Anesthesia in elective orthopedic surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017042333615N1
Enrollment
81
Registered
2017-06-30
Start date
2014-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative shivering.

Interventions

Intervention 1: Intervention group A: Ketamin 2mg/kg is administered during surgery to the patients. Intervention 2: Intervention group B: Pethidine 0.5 mg/kg is administered during surgery to the pa
Treatment - Drugs
Intervention group A: Ketamin 2mg/kg is administered during surgery to the patients.
Intervention group B: Pethidine 0.5 mg/kg is administered during surgery to the patients
Intervention group C: Clonidine 0.2 mg is administered orally prior to surgery

Sponsors

Vice Chancellor for research of Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA class I to II; age between 20 to 60 years; BMI less than 30 kg/m2; scheduled for elective lower extremity surgery. Exclusion criteria: History of hyper or hypothyroidism; Parkinson’s disease; massive blood transfusion; psychiatric disorders; hypothermia38; alcoholism; tremor

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post-operative shivering. Timepoint: 0,5,10,15,20 minutes in recovery room. Method of measurement: Asking and observing patient.

Secondary

MeasureTime frame
Systolic and diastolic blood pressure. Timepoint: 0.5, 10, 15 and 20 minutes after surgery in recovery room. Method of measurement: monitoring.;Postoperation pulse oxymetery. Timepoint: 0.5, 10, 15 and 20 minutes after surgery in recovery room. Method of measurement: monitoring.;Heart rate. Timepoint: 0.5, 10, 15 and 20 minutes after surgery in recovery room. Method of measurement: monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahshid Ghasemi

Shahid Beheshti University of Medical Sciences

mahshidghasemi@sbmu.ac.ir+98 21 2243 2588

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026