Perennial allergic rhinitis. Other allergic rhinitis
Conditions
Interventions
Intervention 1: In Intervention group received Extract drops of mite via sublingual administration for 6 months. Intervention 2: In control group received placebo via for 6 months.
Treatment - Drugs
Placebo
In Intervention group received Extract drops of mite via sublingual administration for 6 months
In control group received placebo via for 6 months
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:approved clinical perennial allergic rhinitis and laboratory diagnosis;the desire of patients to drug treatment and participation in the project Exclusion criteria: Suffering from seasonal allergic rhinitis, a history of autoimmune disease, Consumption of corticosteroids or immunosuppressive drugs, pregnancy, allergic asthma, malnutrition
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms of allergic rhinitis. Timepoint: After six month. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| FOXP3 gene expression. Timepoint: After six month. Method of measurement: Real-Time PCR.;Interlukin-10. Timepoint: After six month. Method of measurement: Real-Time PCR.;Tumor Groeth Factor-B. Timepoint: After six month. Method of measurement: Real-Time PCR.;Interlukin-17. Timepoint: After six month. Method of measurement: Real-Time PCR. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHoma sadri
Mashad Universityof Medcal Sciences
Outcome results
None listed