Gestational diabetes. Diabetes mellitus in pregnancy, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Multi mineral-vitamin D supplements (Vitane, Wolfratshausen, Germany), 400 mg calcium, 100 mg magnesium, 4 mg zinc, 200 IU vitamin D3, daily, for 6 weeks orally. In
Sponsors
Vice chancellor for research, Arak University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Pregnant women aged 18-40 years Diagnosed with GDM at 24-28 weeks' gestation
Exclusion criteria
Exclusion criteria: History of placenta abruption Pre-eclampsia Eclampsia Hypo and hyperthyroidism Kidney or liver diseases Taking magnesium, zinc, calcium and vitamin D supplements prior to intervention Being smoker Insulin therapy after GDM diagnosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hs-CRP. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: ELISA kit.;Total nitrite. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: Spectrophotometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total antioxidant. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: Spectrophotometry.;Malondialdehyde. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: Spectrophotometry.;Glutathione. Timepoint: At the beginning of the study and after 6 weeks of intervention. Method of measurement: Spectrophotometry.;Newborn length. Timepoint: The first 24 h after birth. Method of measurement: Scale.;Newborns' weight. Timepoint: The first 24 h after birth. Method of measurement: Scale.;Polyhydramnios. Timepoint: After the intervention. Method of measurement: Sonography.;Newborn's head circumference. Timepoint: Delivery time. Method of measurement: Tape.;Newborn's bilirubin. Timepoint: Delivery time. Method of measurement: Enzymatic kit.;Apgar score. Timepoint: Delivery time. Method of measurement: Clinical observation.;Preterm delivery. Timepoint: After delivery. Method of measurement: Medical record.;Maternal pre-eclampsia. Timepoint: After delivery. Method of measurement: Medical record.;Maternal hospitalization. Timepoint: After delivery. Method of measurement: Medical record.;Newborns' hospitalization. Timepoint: After delivery. Method of measurement: Medical record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZatollah Asemi
Kashan University of Medical Sciences
Outcome results
None listed