Patients undergoing elective Septorhinoplasty. Congenital malformation of nose, unspecified
Conditions
Interventions
Intervention 1: Intervention group: In the group of magnesium sulfate, magnesium sulfate 50% as a bolus dose and after that, its infusion will be pescribed and continue until the end of surgery. Int
Treatment - Drugs
Intervention group: In the group of magnesium sulfate, magnesium sulfate 50% as a bolus dose and after that, its infusion will be pescribed and continue until the end of surgery.
Control group: an isotonic solution will be used in the same volume.
Sponsors
Vice Chancellor for research of Guilan university of medical sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : age 18 to 50 years old; ASA I,II; Elective Septorhinoplasthy under general anesthesia Exclusion criteria : history of heart or lung disease; Known allergy to magnesium or other drugs used in the study; Hematologic Diseases; severe obesity; neuromuscular disorders, diabetic neuropathy; pregnancy; history of taking ca-blockers, opioids or anticoagulant; Patients who have used magnesium supplements; Anemia (Hemoglobin less than 10 grams per deciliter ) ; Heart rate less than 60 Beats Per Minute; Atrioventricular Blocks; Rejection by patient
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SAP ( Systolic Arterial Pressure) , HR (Heart Rate) , MAP (Mean Arterial Pressure). Timepoint: First before Induction and then immediately after induction and then every 5 minutes until the end of the surgery will be monitored. Method of measurement: All patients will be positioned in the 30 degree head up during surgery and noninvasive blood pressure will be measured from the patient's arm.;Intraoperative bleeding. Timepoint: During Surgery every 5 minute. Method of measurement: Intraoperative blood loss (per mililiter) will be measured by counting the number of blood gases in addition to blood in the suction device. The amount of acceptable bleeding will be calculated by MABL formula and then compare with the amount of intraoperative bleeding (Less than 10% of the acceptable bleeding, Between 10 to 20 % and more than 20%).;Length of surgery and Surgeon's satisfaction. Timepoint: After Surgery. Method of measurement: The duration of surgery is calculated per minute after surgery. Surgeon's satisfaction of the surgical field after practice will be evaluated from 0 to 10 by Beozaart test.;Patient’s pain level and serum magnesium level. Timepoint: The patient's pain level will be evaluated every 10 minute after surgery indecently after arriving in PACU. Serum magnesium level in all patients will be evaluted at the end of the surgary, before extubation. Method of measurement: Patients will be asked to show their pain levels on the Visual Analog Scale every 10 minute Until discharge from PACU. Serum magnesium levels will be evaluated by sending blood sample to the laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Shideh Marzban
Amiralmomenin Hospital
Outcome results
None listed