Skip to content

Effect of Local Fibrinogen Administration on postoperative bleeding in open Prostatectomy surgery

Effect of Local Fibrinogen Administration on postoperative bleeding in open Prostatectomy surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170421033564N1
Enrollment
44
Registered
2018-01-21
Start date
2018-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Prostate Hypertrophy. Enlarged Prostate

Interventions

Intervention 1: Intervention group: Drug : Fibrinogen Dose: 500 mg Number of using: Once Factory name: CSL Behring Company Manufacturing Country's Name: USA Location prescribed: Local Administration
Prevention
Placebo
Intervention group: Drug : Fibrinogen Dose: 500 mg Number of using: Once Factory name: CSL Behring Company Manufacturing Country's Name: USA Location prescribed: Local Administration time: End of Sur
Control group: Placebo: Normal Saline: Dose: 10 MilliliterNumber of using: OnceFactory name: Abureihan CompanyManufacturing Country's Name: IranLocation prescribed: LocalAdministration time End of sur

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients candidate for elective open prostatectomy surgery, Preoperative serum fibrinogen level between 2-4 g/l, ASA I,II , Age 45-70y

Exclusion criteria

Exclusion criteria: Exclusion criteria: Emergent or urgent surgery; Age more than 70 years or less than 45 years old; History of deep vein thrombosis; History of underlying hematologic disorders

Design outcomes

Primary

MeasureTime frame
Bleeding during and after Prostatectomy surgery. Timepoint: End of surgery and 24 hours after surgery. Method of measurement: Observe.

Secondary

MeasureTime frame
Volume of administered blood product. Timepoint: Twenty four hours after surgery. Method of measurement: Milliliter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Reza Ghandizadeh Dezfuli

Ahvaz University of Medical Sciences

ghandizadehdezfuli.m@ajums.ac.ir+98 61 1356 9857

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026