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Evaluation the effects of antioxidants on sperm molecular chromatin in recurrent pregnancy loss

Evaluation the effects of antioxidants on sperm molecular chromatin in recurrent pregnancy loss

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201704195261N3
Enrollment
90
Registered
2017-05-08
Start date
2017-05-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent pregnancy loss. habitual or recurrent N96 without current pregnancy N96 Loss (of) pregnancy

Interventions

Intervention 1: control. Intervention 2: vit E(400 mg)+ selenium(200 mg), daily. 3 months. Intervention 3: vit E(400 mg)+ zinc(30 mg), daily, 3 months.
Lifestyle
Treatment - Drugs
control
vit E(400 mg)+ selenium(200 mg), daily. 3 months
vit E(400 mg)+ zinc(30 mg), daily, 3 months

Sponsors

Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 49 Years

Inclusion criteria

Inclusion criteria: All couples with recurrent pregnancy loss included. varicocele, Cryptorchidism, addicted male and heavy smokersT up of 50 years old male excluded from study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sperm count. Timepoint: 3 months. Method of measurement: 2010WHO Guidelines.;Sperm motility. Timepoint: 3 months. Method of measurement: 2010 WHO Guidelines.;Sperm morpholigy. Timepoint: 3 months. Method of measurement: 2010 WHO Guidelines.;Dna fragmentation. Timepoint: 3 months. Method of measurement: 2010 WHO Guidelines.;Protamine ratio. Timepoint: 3 months. Method of measurement: 2010 Who Guidelines.;Histone ratio. Timepoint: 3 montha. Method of measurement: 2010 WHO Guidelines.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheila Pourmasumi

Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences

spourmasumi@yahoo.com+98 35 3824 7087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026