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Acute Normovolomic Hemodilution effect on the amount of bleeding after Coronary Artery Bypass Grafting surgery in the first 48 hours postoperative

Acute Normovolomic Hemodilution effect on the amount of bleeding after Coronary Artery Bypass Grafting surgery in the first 48 hours postoperative

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041933529N1
Enrollment
100
Registered
2017-08-07
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery bypass graft. unspecified coronary artery bypass graft

Interventions

Intervention 1: Intervention group: After induction of anesthesia in the operating room and before connecting the patient to the CPB pump, a blood unit is taken from patients in the intervention group
Treatment - Other
Intervention group: After induction of anesthesia in the operating room and before connecting the patient to the CPB pump, a blood unit is taken from patients in the intervention group. After completi
Control group: No intervention will be given in the control group.

Sponsors

Vice chancellor for research, Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: No previous known history of coagulation disorders; No previous treatment with drugs used in coagulation disorders. Exclusion criteria: Anemia (hemoglobin less than 11); Massive transfusion (more than 1 blood volume or 20 packed cell); Platelet transfusion; FFP transfusion; Receiving medications such as Plavix and Transamine; Connection to the CPB pump more than 3 houres; platelet count less than 100 thousand.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Amount of bleeding. Timepoint: 36 measurements in 2-hour intervals (12 times per day, in the first 3 days). Method of measurement: by graduated drains (in terms of mL).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Khajavi

Ardabil University Of Medical Sciences

S.khajoo@arums.ac.ir+98 455512006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026