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Effect of Lemon balm on anxiety

Effects of Melissa officinalis extract on the level of anxiety in patients with leukemia: a randomized, double-blind, placebo-controlled clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041926804N2
Enrollment
70
Registered
2017-06-19
Start date
2017-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety. Anxiety disorder, unspecified

Interventions

Intervention 1: Intervention group: Melissa officinalis (Lemon balm) extract, 300 mg cap, BID, 8 weeks. Intervention 2: Control group:placebo, 300 mg cap, BID, 8 weeks.
Treatment - Drugs
Placebo
Intervention group: Melissa officinalis (Lemon balm) extract, 300 mg cap, BID, 8 weeks
Control group:placebo, 300 mg cap, BID, 8 weeks

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: age between 18 to 60 years old; patients with new recognized leukemia; patients with anxiety; patients who take one SSRI beside the intervention; no pregnancy; no lactation; no other anti-anxiety herbal drug administration.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Beck anxiety Score. Timepoint: before intervention, 2,4 and 8 weeks after intervention. Method of measurement: Beck anxiety intervention.

Secondary

MeasureTime frame
Treatment response. Timepoint: at the end of week 8 after intervention. Method of measurement: =50% improvement in mean Beck Anxiety Inventory score.;Treatment response. Timepoint: at the end of week 8 after intervention. Method of measurement: difference of mean Beck anxiety score from baseline (treatment response is defined as =50% improvement).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ayati

Department of traditional madicine , School of Pharmacy, Mashhad University of Medical Sciences, Mas

ayatiz941@mums.ac.ir+98 51 31801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026